Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Larvicidal diterpenes from Pterodon polygalaeflorus.

M C De Omena1, E S Bento, J E De Paula

  • 1Departamento de Química, Universidade Federal de Alagoas, Maceió-AL, Brazil.

Vector Borne and Zoonotic Diseases (Larchmont, N.Y.)
|June 27, 2006
PubMed
Summary

Ethanolic extract from Pterodon polygalaeflorus seeds shows larvicidal activity against Aedes aegypti mosquitoes. Three diterpenoid furan compounds were isolated and identified, demonstrating significant mosquito larvicidal properties.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Energy production pathways of female soccer players during championships: a metabolomics approach.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2026
Same author

Metabolomic profiles and antioxidant intake in female soccer players: a cross-sectional study.

European journal of applied physiology·2025
Same author

Effects of long-term metformin administration associated with high-intensity interval training on physical performance, glycogen concentration, GLUT-4 content, and NMR-based metabolomics in healthy rats.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2024
Same author

Molecular docking studies and evaluation of the antiretroviral activity and cytotoxicity of the species Lafoensia pacari Saint-Hilaire.

Brazilian journal of biology = Revista brasleira de biologia·2022
Same author

Cytotoxic activity of naphthoquinones with special emphasis on juglone and its 5-O-methyl derivative.

Chemico-biological interactions·2010
Same author

Larvicidal activities against Aedes aegypti of some Brazilian medicinal plants.

Bioresource technology·2006

Area of Science:

  • Natural Product Chemistry
  • Medical Entomology
  • Organic Chemistry

Background:

  • Aedes aegypti mosquitoes are significant vectors of diseases like dengue and Zika.
  • Natural products are a promising source for novel insecticides.
  • Pterodon polygalaeflorus is a plant species with potential medicinal properties.

Purpose of the Study:

  • To investigate the larvicidal activity of Pterodon polygalaeflorus seed extract against Aedes aegypti.
  • To isolate and characterize active compounds from the extract.
  • To evaluate the efficacy of isolated compounds as mosquito larvicides.

Main Methods:

  • Bioassay-guided fractionation of ethanolic seed extract.
  • Structure elucidation using spectroscopic techniques (IR, UV, NMR, Mass Spectrometry).

Related Experiment Videos

  • Determination of lethal concentration 50 (LC50) values against Aedes aegypti larvae.

    • Main Results:

    • Isolation of three known diterpenoid furans: 6alpha-hydroxyvouacapan-7beta,17beta-lactone (1), 6alpha,7beta-dihydroxyvouacapan-17beta-oic acid (2), and methyl 6alpha,7beta-dihydroxyvouacapan-17beta-oate (3).
    • Compounds 1, 2, and 3 exhibited LC50 values of 50.08, 14.69, and 21.76 microg/mL, respectively.
    • Full NMR assignments were provided for compounds 1-3 and a derivative.

    Conclusions:

    • The ethanolic extract of Pterodon polygalaeflorus seeds contains compounds with potent Aedes aegypti larvicidal activity.
    • Diterpenoid furans isolated from this plant represent potential candidates for developing new mosquito control agents.
    • Further research into these compounds could lead to environmentally friendly larvicides.