Related Experiment Video
Updated: Aug 7, 2026

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
[Estimation of overall cardiovascular risk from coronary risk. A cohort study]
José Miguel Baena-Díez1, Manel García-Lareo, Marian de la Poza-Abad
1ABS Dr. Carles Ribas-La Marina, Institut Català de la Salut, Barcelona, España. jbaenad@meditex.es
Insights
Coronary risk (CR) is not a reliable predictor of global cardiovascular risk (GCR). A new equation is needed to accurately estimate GCR, as multiplying CR by 1.3 is insufficient.
Area of Science:
- Cardiology
- Epidemiology
- Public Health
Context:
- Cardiovascular disease (CVD) poses a significant global health burden.
- Accurate risk assessment is crucial for effective prevention strategies.
- Existing models for global cardiovascular risk (GCR) require validation in diverse populations.
Purpose:
- To evaluate the accuracy of coronary risk (CR) as a proxy for GCR.
- To determine the appropriate multiplier for estimating GCR from CR in a specific population.
- To highlight the need for refined cardiovascular risk assessment tools.
Summary:
- A 5-year prospective cohort study followed 851 adults (35-74 years) without CVD.
- The study found the accumulated incidence of CR was 2.5% and GCR was 5.2%.
- Estimating GCR requires multiplying CR by 2.1, not the previously suggested 1.3.
Impact:
- Coronary risk alone is an inadequate measure of global cardiovascular risk.
- Current risk prediction models may overestimate or underestimate actual GCR.
- Development of a more precise GCR equation is necessary for improved patient management and public health interventions.
Background And Objective:
The coronary risk (CR) is a good approximation of the global cardiovascular risk (GCR). Multiplying the CR per 1.3 we obtain the GCR, but we don't know if it is certain in our country.
Patients And Method:
Prospective cohort study with 851 patients of ages between 35-74 years old, without cardiovascular disease and followed during 5 years. CR include myocardial ischemia (angor pectoris or myocardial infarction). GCR include CR, cerebrovascular disease, and peripheral vascular disease.
Results:
We registered 21 myocardial ischemia cases, 15 cerebrovascular disease cases and 8 peripheral vascular disease cases. The accumulated incidence was: 2.5% for CR and 5.2% for GCR (difference 2.7%; 95% confidence interval for the difference 0.9-4.6%; p < 0.05). To estimated GCR we should multiple CR per 2.1.
Conclusions:
CR is not a good approximation of GCR. We need to developed equation that include not only CR but also GCR.
Related Concept Videos
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Coronary Artery Disease IV: Preventive Measures
Coronary Artery Disease I: Introduction
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...