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Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
Published on: November 7, 2020
Renal impairment after living donor liver transplantation
N Akamatsu1, Y Sugawara, S Tamura
1Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan.
Background:
There are few reports of postoperative renal impairment after living donor liver transplantation (LDLT).
Methods:
We reviewed 246 LDLT recipients to examine the effects of postoperative renal impairment on the results of LDLT.
Results:
The incidence of renal impairment and the requirements for postoperative renal replacement therapy were 29% and 9%, respectively. Intraoperative blood loss (P<.0001) and preoperative serum creatinine (P=.0002) were significant independent risk factors for the development of early renal dysfunction. Patients who required renal replacement therapy had a lower survival rate (P=.01).
Conclusions:
We identified the risk factors for postoperative renal impairment, providing useful metrics to establish a treatment strategy for high risk liver transplant patients.
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