Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microbial adhesion to zirconium alloys.

J D Ehrman1, E T Bender, N Stojilovic

  • 1Department of Physics, The University of Akron, Akron, OH 44325, United States.

Colloids and Surfaces. B, Biointerfaces
|June 27, 2006
PubMed
Summary

Microbial adhesion to zirconium implants like Zircaloy-2 and Zircadyne-705 was studied. Surface oxide thickness predicts bacterial and yeast adherence, crucial for joint replacement safety.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Technical Aspects of a National Service for Paediatric Pelvic Brachytherapy.

Clinical oncology (Royal College of Radiologists (Great Britain))·2024
Same author

Immunotolerance of dairy heifers in response to repeated exposure to bacterial lipopolysaccharide endotoxin.

Veterinary immunology and immunopathology·2023
Same author

A National Referral Service for Paediatric Brachytherapy: An Evolving Practice and Outcomes Over 13 Years.

Clinical oncology (Royal College of Radiologists (Great Britain))·2023
Same author

Metals in urban soils of Europe: A systematic review.

The Science of the total environment·2022
Same author

Response to Jackson and Harris, 2022;179:102417.

Prostaglandins, leukotrienes, and essential fatty acids·2022
Same author

Dynamic changes in Holstein heifer circulatory stress biomarkers in response to lipopolysaccharide immune challenge.

Veterinary immunology and immunopathology·2022

Area of Science:

  • Biomaterials Science
  • Microbiology
  • Surface Chemistry

Background:

  • Zirconium-based alloys (Zircaloy-2, Zircadyne-705) are used in orthopedic implants.
  • Microbial adhesion to implant surfaces is a critical factor in implant-associated infections.
  • Understanding adherence of common pathogens like Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Candida albicans is essential.

Purpose of the Study:

  • To investigate the adhesion of clinically relevant bacteria and yeast to Zircaloy-2 and Zircadyne-705 surfaces.
  • To determine the influence of surface oxide thickness on microbial adhesion.
  • To develop a predictive model for microbial adhesion based on surface characteristics.

Main Methods:

  • Utilized clinical strains of Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Candida albicans.

Related Experiment Videos

  • Employed shaken and stationary exposure conditions on Zircaloy-2 and Zircadyne-705 surfaces with varying oxide thicknesses.
  • Applied X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), viable counts, and endotoxin assays for analysis.

    • Main Results:

    • Demonstrated differential adhesion of bacteria and yeast to the zirconium alloy surfaces.
    • Established a correlation between surface oxide thickness and the extent of microbial adhesion.
    • Developed a predictive model for microbial adhesion using XPS data, showing potential for surface characterization.

    Conclusions:

    • Surface properties, particularly oxide thickness, significantly influence microbial adhesion to zirconium-based biomaterials.
    • The findings provide insights into preventing implant-associated infections by optimizing implant surface characteristics.
    • A predictive XPS-based model offers a valuable tool for assessing the bioadhesion potential of zirconium surfaces.