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Updated: Aug 7, 2026
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A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
[Maternal-fetal staphylococcal toxic shock syndrome with chorioamniotitis]
A Lacoste1, A Torregrosa, S Dubois
1Service de pédiatrie et néonatologie, centre hospitalier de la Côte-Basque, 13, avenue Interne-J.-Loëb, 64100 Bayonne, France.
Summary
This case study details a rare mother-infant Staphylococcal Toxic Shock Syndrome (TSS) diagnosis. Early recognition of staphylococcal infection symptoms like rash and shock is crucial for prompt treatment in neonates.
Area of Science:
- Neonatal Medicine
- Infectious Diseases
- Toxicology
Background:
- Staphylococcal Toxic Shock Syndrome (TSS) is a rare but severe condition.
- Maternal septic syndrome during pregnancy poses risks to the neonate.
- Early diagnosis and intervention are critical for managing TSS.
Observation:
- A term neonate presented with respiratory distress, pulmonary hypertension, rash, and multi-organ involvement post-cesarean section.
- Staphylococcus aureus was identified in the neonate from placenta, swabs, and gastric aspirate.
- The mother also exhibited symptoms including shock, rash, and inflammatory syndrome.
Findings:
- The neonate and mother were diagnosed with Staphylococcal TSS.
- The Staphylococcus aureus isolate produced enterotoxins C and L.
- Both mother and infant received appropriate treatment, including antibiotics and respiratory support, with favorable outcomes.
Implications:
- Suspected TSS in neonates with staphylococcal infections presenting with shock, rash, and multi-organ failure is critical.
- This case highlights the importance of considering TSS in neonates with severe staphylococcal infections.
- Prompt recognition and management can lead to positive outcomes in both mother and infant dyads.
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