Related Experiment Video

Updated: Aug 7, 2026

Auricular Acupressure as an Adjuvant Treatment for Wheezing in Stable Chronic Obstructive Pulmonary Disease
02:34

Auricular Acupressure as an Adjuvant Treatment for Wheezing in Stable Chronic Obstructive Pulmonary Disease

Published on: May 10, 2024

Preschool wheeze prognosis: how do we predict outcome?

LeRoy M Graham1

  • 1Georgia Pediatric Pulmonology Associates, and Morehouse School of Medicine, Suite 450, 1100 Lake Hearn Drive, Atlanta, GA 30319, USA. lmg254@aol.com

Paediatric Respiratory Reviews
|June 27, 2006
PubMed

Insights

Preschool wheezing is common but hard to predict. Identifying distinct phenotypes is key for effective treatment and prognosis in children.

Area of Science:

  • Pediatrics
  • Respiratory Medicine
  • Clinical Phenotyping

Background:

  • Preschool wheezing is a frequent condition in children.
  • Determining the prognosis for preschool wheezing is challenging.
  • This condition is associated with significant morbidity and healthcare resource utilization.

Purpose of the Study:

  • To review the clinical presentation, etiologies, and triggers of preschool wheezing.
  • To identify historical, hereditary, and laboratory markers for diagnosis and management.
  • To aid clinicians in differentiating preschool wheezing phenotypes for tailored care.

Main Methods:

  • Review of clinical presentations.
  • Analysis of potential etiologies and triggers.
  • Evaluation of diagnostic and management markers.

Main Results:

  • Preschool wheezing may present as at least three distinct phenotypes.
  • Each phenotype has unique clinical significance and therapeutic implications.
  • Accurate phenotype identification guides family education, therapy, and prognosis.

Conclusions:

  • Differentiating preschool wheezing phenotypes is crucial for optimal patient management.
  • Understanding phenotypes improves therapeutic strategies and prognostic accuracy.
  • This review provides a framework for diagnosing and managing preschool wheezing.

Related Concept Videos

Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
Introduction to Language of Pathophysiology ll01:17

Introduction to Language of Pathophysiology ll

This lesson explores key terms that describe how diseases progress, their outcomes, and their distribution in populations.Diagnostic tests identify diseases and monitor treatment. These include blood and urine tests, biopsies, imaging (X-ray, MRI), and detection of infectious agents.Remission is a reduction or disappearance of symptoms.Exacerbation refers to the worsening of symptoms, such as increased wheezing during an asthma attack.A precipitating factor triggers an acute episode, while a...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...