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Updated: Aug 7, 2026

Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease
Published on: April 12, 2021
Disorders of lung morphogenesis
1Division of Pulmonary Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, MLC 7029, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA. jeff.whitsett@cchmc.org
Abstract:
Perinatal lung function depends upon formation of the conducting and gas exchange regions of the lung. The precise expression of transcription factors and signaling molecules is required for normal lung morphogenesis.
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