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Updated: Aug 7, 2026
11:51
Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
Published on: March 2, 2011
Testosterone and doping control
C Saudan1, N Baume, N Robinson
1Swiss Laboratory for Doping Analyses, Institute of Legal Medicine, Lausanne, Switzerland. martial.saugy@chuv.ch
British Journal of Sports Medicine
|June 27, 2006
Summary
Anabolic steroid detection in athletes uses gas chromatography-mass spectrometry and isotope ratio analysis. New methods are needed to detect long-term oral testosterone use due to rapid pharmacokinetics.
Area of Science:
- Sports Science
- Analytical Chemistry
- Pharmacology
Background:
- Anabolic steroids are synthetic testosterone derivatives banned in sports.
- Detection methods must distinguish between natural and administered testosterone.
- Adverse effects and banned status necessitate reliable doping detection.
Purpose of the Study:
- To review anabolic-androgenic steroid use in sports.
- To overview anti-doping laboratory detection methods for steroids in urine.
- To emphasize testosterone doping detection strategies.
Main Methods:
- Literature review of anabolic steroid testing, athletic use, and adverse effects.
- Analysis of current anti-doping laboratory procedures.
- Focus on gas chromatography-mass spectrometry and isotope ratio analysis.
Main Results:
- Outlined procedures for detecting doping with endogenous steroids.
- World Anti-Doping Agency guidelines ensure uniform reporting of abnormal steroid profiles.
- Detection methods address testosterone, its precursors, and masking agents.
Conclusions:
- Current technology is suitable for detecting intramuscular testosterone administration.
- Oral testosterone administration requires urine collection within hours of intake due to rapid pharmacokinetics.
- Development of specific biomarkers for long-term oral testosterone detection is needed.
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