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Metastases of the digestive tract and ovarian tumors--or vice versa: an analysis

M Gojnic1, V Dugalic, V Jeremic

  • 1Institute of Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade University, Serbia and Montenegro.

European Journal of Gynaecological Oncology
|June 28, 2006
PubMed

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...