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Genital tuberculosis and subsequent fertility.
1Department of Obstetrics and Gynaecology, St. George's Hospital, London, UK.
Summary
Genital tuberculosis significantly impacts fertility, with live births being rare even after treatment. Assisted reproductive technologies like in vitro fertilization offer a potential, albeit limited, solution for achieving pregnancy.
Area of Science:
- Reproductive Medicine
- Infectious Diseases
- Tuberculosis Research
Background:
- Genital tuberculosis (GTB) poses a significant challenge to female fertility.
- Effective treatment for tuberculosis does not guarantee restoration of reproductive function.
Purpose of the Study:
- To evaluate the fertility outcomes following treatment for genital tuberculosis.
- To assess the success rates of various treatment modalities, including assisted reproductive technologies.
Main Methods:
- Review of treatment outcomes for patients with genital tuberculosis.
- Analysis of fertility rates associated with medical, surgical, and combined therapies.
- Evaluation of the efficacy of in vitro fertilization (IVF) and embryo replacement.
Main Results:
- Successful pregnancy and live birth at term are infrequent after GTB, despite treatment.
- Medical, surgical, or combined treatments are linked to poor fertility outcomes.
- In vitro fertilization has demonstrated success in a limited number of GTB patients.
Conclusions:
- Genital tuberculosis severely compromises fertility, necessitating advanced reproductive assistance.
- While challenging, assisted reproductive technologies like IVF present a viable option for selected GTB patients seeking to conceive.