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Updated: Aug 7, 2026

A Mass Spectrometry-Based Approach to Identify Phosphoprotein Phosphatases and their Interactors
Published on: April 29, 2022
Deciphering signaling control by phosphoproteome using mass spectrometry
1Department of Surgery, Division of Urology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. leungyk@ucmail.uc.edu
Abstract:
Analysis of changes in genes and protein profiles provides invaluable information to understand the activities and functions of proteins. However, their activities are further regulated by post-translational modifications, such as glycosylation and phosphorylation. Cell growth and apoptotic pathways are good examples of demonstrating the roles of phosphorylation in activation of protein cascades upon stimulation.
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