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Movement disorders and alcohol misuse.

Christopher W Hess1, Rachel Saunders-Pullman

  • 1Department of Neurology, Albert Einstein College of Medicine, USA.

Addiction Biology
|June 28, 2006
PubMed
Summary
This summary is machine-generated.

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Alcohol abuse is complexly linked to essential tremor (ET) and myoclonus-dystonia (M-D). This review explores alcohol

Area of Science:

  • Neurology
  • Neuropharmacology
  • Movement Disorders

Background:

  • Substance abuse can cause various movement disorders like tics, chorea, tremor, myoclonus, and parkinsonism.
  • Alcohol exhibits a complex association with essential tremor (ET) and myoclonus-dystonia (M-D).
  • Understanding this link may reveal new therapeutic strategies.

Purpose of the Study:

  • To review the comorbidity of alcohol abuse in ET and M-D.
  • To examine the ameliorative effects of alcohol in ET and M-D.
  • To explore alcohol abuse as self-medication in these disorders.
  • To discuss shared pathophysiologic mechanisms.

Main Methods:

  • Literature review of studies on alcohol abuse and movement disorders.
  • Analysis of data on self-medication patterns in ET and M-D patients.

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  • Discussion of potential shared biological pathways.

    • Main Results:

    • Alcohol abuse is frequently comorbid with ET and M-D.
    • Alcohol consumption appears to temporarily alleviate symptoms in both ET and M-D.
    • Evidence suggests self-medication with alcohol is a significant factor in these patient groups.

    Conclusions:

    • Alcohol's complex relationship with ET and M-D warrants further investigation.
    • Shared pathophysiologic mechanisms may exist between these disorders and alcohol's effects.
    • Elucidating these mechanisms could lead to innovative treatments for ET, M-D, and alcohol-related movement disorders.