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Updated: Aug 7, 2026

Monitoring Stub1-Mediated Pexophagy
Published on: May 12, 2023
Peroxisome biogenesis: the peroxisomal endomembrane system and the role of the ER
Vladimir I Titorenko1, Robert T Mullen
1Department of Biology, Concordia University, Montreal, Quebec H4B 1R6, Canada.
Abstract:
Peroxisomes have long been viewed as semiautonomous, static, and homogenous organelles that exist outside the secretory and endocytic pathways of vesicular flow. However, growing evidence supports the view that peroxisomes actually constitute a dynamic endomembrane system that originates from the endoplasmic reticulum. This review highlights the various strategies used by evolutionarily diverse organisms for coordinating the flow of membrane-enclosed carriers through the peroxisomal endomembrane system and critically evaluates the dynamics and molecular mechanisms of this multistep process.
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