Patient-perceived impact of resective epilepsy surgery

Area of Science:

• Neurosurgery
• Epileptology
• Patient-reported outcomes

Background:

• Resective epilepsy surgery is a significant intervention for drug-resistant epilepsy.
• Evaluating patient-perceived impact is crucial for assessing the success of elective, invasive procedures.

Purpose of the Study:

• To assess the patient-perceived impact of resective epilepsy surgery.
• To identify predictors of positive patient outcomes following epilepsy surgery.

Main Methods:

• A multicenter cohort study involving 396 patients undergoing resective epilepsy surgery.
• Assessed willingness to repeat surgery and overall life impact at 3, 12, and 24 months.
• Multivariate ordinal logistic regression analyzed predictors of perceived impact.

Main Results:

• Over 73% of patients would undergo surgery again, with over 75% reporting a strong positive impact.
• Seizure freedom was a key predictor of positive perceptions at all time points.
• Employment status improvement and female gender were associated with better outcomes; right-sided resection showed positive impact.

Conclusions:

• The majority of patients experience significant positive impact and willingness to repeat resective epilepsy surgery.
• Seizure freedom is strongly linked to favorable patient perceptions.
• Facilitating employment reintegration post-surgery is vital for enhancing overall patient well-being.