Related Experiment Video
Updated: Aug 7, 2026

A Hepatocellular Cancer Patient-Derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth
Published on: February 2, 2024
[Delayed recurrence of an endobiliary hepatocellular carcinoma without detectable intra-parenchymatous tumor]
Eric Vibert1, Denis Chatelain, Corrine Barrucand
1Département de Chirurgie Digestive, Centre Hospitalier et Universitaire Amiens Nord Université de Picardie.
Abstract:
Obstructive jaundice is uncommon in patients with hepatocellular carcinoma. It can be due to compression of the common bile duct by the liver tumor or by enlarged lymph node metastases in the porta hepatis. Obstructive jaundice can also be due to direct extension of hepatocellular carcinoma into the bile ducts with or without a detectable primary hepatic tumor. These particular hepatocellular carcinoma have been termed "icteric type hepatoma" by Lin et al. in 1975, who emphasized their poor prognosis. We report a similar case of endobiliary hepatoma without a detectable intraparenchymal hepatic tumor in a seventy year-old man. This case is unusual because of its positive evolution and late recurrence.