Is infant growth changing?

A R Tate1, C Dezateux, T J Cole

  • 1Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, London, UK. rosemary.tate@iop.kcl

Insights

Infant weight gain from birth to 9 months varies by ethnicity, with Black infants gaining the most and Asian infants the least. Childhood obesity likely begins after 9 months, not during this early period.

Area of Science:

  • Pediatric growth and development
  • Public health and epidemiology
  • Childhood obesity research

Background:

  • Understanding infant growth patterns is crucial for identifying potential health risks.
  • Previous studies indicate variations in infant weight gain based on demographic factors.
  • The rising prevalence of childhood obesity necessitates investigation into early life factors.

Purpose of the Study:

  • To analyze weight gain differences in infants up to 9 months by sex, ethnicity, and country of birth.
  • To compare current infant weight gain with a cohort from a decade prior.
  • To assess the onset of the childhood obesity epidemic in relation to early infant growth.

Main Methods:

  • Analysis of weight and weight gain data from 12,903 term infants in the Millennium Cohort Study.
  • Standardized weight and weight gain comparisons between ethnic groups and countries of birth.
  • Longitudinal comparison with a historical cohort of infants born 10 years earlier.

Main Results:

  • Significant ethnic variations in weight gain were observed; Black infants showed the highest, and Asian infants the lowest.
  • White boys in England and Scotland exhibited faster growth than girls; no significant gender differences were found in other groups or locations.
  • Minimal difference in weight gain between current and historical white English infant cohorts.

Conclusions:

  • Early infant weight gain (0-9 months) shows significant ethnic and geographical variations.
  • Current infant growth patterns do not differ substantially from a decade ago, suggesting later onset of obesity.
  • The childhood obesity epidemic appears to emerge after the first 9 months of life.

Related Concept Videos

Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience, such as differences...
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Rate of Change: Problem Solving01:26

Rate of Change: Problem Solving

Temperature-Dependent Growth of Brook TroutThe growth of brook trout is closely influenced by water temperature. Experimental data demonstrate how trout weight changes over a 24-day period in response to varying water temperatures. At lower temperatures, such as 15.5 degrees Celsius, brook trout show significant weight gain. However, as the temperature increases, the amount of weight gained steadily decreases. At the highest temperature measured, 24.4 degrees Celsius, trout experience a net...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Population Growth00:57

Population Growth

Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.However, realistic environmental conditions limit the number of...