Related Experiment Video
Updated: Aug 7, 2026

Quantifying Inferior Vena Cava Compliance and Distensibility in an In Vivo Ovine Model Using 3D Angiography
Published on: April 26, 2024
Vasovist-enhanced MR angiography
Mathias Goyen1, Kohkan Shamsi, Stefan O Schoenberg
1University Medical Center, Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany. goyen@uke.uni-hamburg.de
Abstract:
Vasovist (MS-325) is the first intravascular contrast agent approved for use with magnetic resonance angiography in the European Union. Vasovist reversibly binds to albumin, providing extended intravascular enhancement compared to existing extracellular magnetic resonance contrast agents. Prior to approval, Vasovist underwent extensive testing to evaluate the safety and efficacy of the drug; the clinical trials program included blinded, placebo-controlled dose ranging, efficacy in a variety of vascular beds (AIOD, renal, pedal), examination of potential drug interaction with warfarin and comparison with XRA. The clinical trials show that Vasovist-enhanced MR angiography is safe and well-tolerated in patients with vascular disease, effective for the detection of vascular stenosis and aneurysms, significantly more accurate (both more sensitive and specific) than non-contrast MR angiography for the diagnosis of vascular stenoses, and similar to conventional angiography for the overall characterization of vascular disease, without the need for catheterization.
Related Concept Videos
Imaging Studies VII: Vascular Imaging
Imaging Studies for Cardiovascular System IV: CMRI
Imaging Studies for Cardiovascular System V: CT
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

