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Related Experiment Videos

Review article: intestinal failure.

S Lal1, A Teubner, J L Shaffer

  • 1Intestinal Failure Unit, Hope Hospital, Salford, UK.

Alimentary Pharmacology & Therapeutics
|June 29, 2006
PubMed
Summary
This summary is machine-generated.

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Intestinal failure occurs when the body cannot absorb nutrients. Type 2 intestinal failure requires a multidisciplinary approach for management, involving nutritional support and addressing complications to prevent long-term parenteral nutrition dependence.

Area of Science:

  • Gastroenterology
  • Clinical Nutrition
  • Surgical Science

Background:

  • Intestinal failure is defined by the inability to maintain nutrient balance due to intestinal resection or malabsorption.
  • It presents in varied forms, including self-limiting Type 1 and more complex Type 2, often following surgery for conditions like Crohn's disease.

Purpose of the Study:

  • To review the causes and management of intestinal failure.
  • To highlight the critical need for a multidisciplinary approach in managing Type 2 intestinal failure.

Main Methods:

  • A MEDLINE search was conducted from 1966 to 2006.
  • Keywords included "intestinal failure," "parenteral nutrition," "enteral nutrition," "intestinal fistula," and "short bowel syndrome."

Main Results:

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  • Type 1 intestinal failure is common after abdominal surgery, requiring short-term support.
  • Type 2 intestinal failure involves severe complications and necessitates comprehensive management before surgical reconstruction.
  • A structured approach can prevent progression to Type 3 intestinal failure, defined by long-term parenteral nutrition dependency.

Conclusions:

  • Effective management of Type 2 intestinal failure is crucial for patient outcomes.
  • A multidisciplinary strategy is essential for nutritional repletion and complication management.
  • Preventing progression to long-term parenteral nutrition is a key goal in treating complex intestinal failure.