Related Experiment Video
Updated: Aug 7, 2026

Measurements of Physiological Stress Responses in C. Elegans
Published on: May 21, 2020
Heat-shock protein 70 genes and human longevity: a view from Denmark
Ripudaman Singh1, Steen Kølvraa, Peter Bross
1Department of Human Genetics, Bartholin Building, University of Aarhus, Denmark. singh@humgen.au.dk
Abstract:
We have studied the association of three single nucleotide polymorphisms (SNPs) present in the three HSP70 (heat-shock protein) genes on 6p21 with human longevity. The availability of biological samples from various population cohorts in Denmark has given us the opportunity to try novel methods of gene association with human longevity. A significant association of one haplotype with male longevity was observed. Furthermore, a significant difference in the survival of the carriers of the different genotypes in females was observed. We also found an age-dependant decline in the ability of peripheral blood mononuclear cells to respond to heat stress in terms of Hsp70 induction.
Related Concept Videos
Telomeres and Telomerase
Telomeres and Telomerase
Bacterial Protein Maturation

