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Updated: Aug 7, 2026

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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Hypomania as an aura in migraine
Soumitra Shankar Datta1, Sudhir Kumar
1Department of Psychiatry, Royal Cornhill Hospital, Aberdeen, UK.
Neurology India
|June 29, 2006
Summary
A case study highlights classic migraine with hypomanic aura in a young man. Treatment with valproate, a mood stabilizer, effectively reduced episodic headaches and behavioral symptoms.
Area of Science:
- Neurology
- Psychiatry
Background:
- Migraine is a common neurological disorder.
- Affective symptoms are frequently observed in migraine patients.
Observation:
- A 19-year-old man presented with episodic headaches and prominent behavioral symptoms.
- A diagnosis of classic migraine with hypomanic aura was established.
- Valproate therapy was initiated for the affective symptoms within the aura.
Findings:
- Valproate treatment led to a gradual decrease in headache frequency.
- The patient remained symptom-free during a 2-year follow-up.
- This case suggests a potential link between migraine aura and mood disturbances.
Implications:
- The findings may offer new insights into the pathophysiology of mood disorders.
- Further research into the neurobiological mechanisms of migraine aura and mood symptoms is warranted.
- Mood stabilizers could be a potential therapeutic option for specific migraine presentations.
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