Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Infections associated with orthopedic implants.

Andrej Trampuz1, Andreas F Widmer

  • 1Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Basel, Switzerland.

Current Opinion in Infectious Diseases
|June 29, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adverse events and tolerability of long-term suppressive antibiotic therapy for periprosthetic joint infection: a prospective cohort study.

Journal of bone and joint infection·2026
Same author

Correction: Pérez-Prieto et al. Are Hamstring Grafts a Predisposing Factor to Infection in R-ACL Surgery? A Comparative In Vitro Study. <i>Pathogens</i> 2023, <i>12</i>, 761.

Pathogens (Basel, Switzerland)·2026
Same author

Position statement: integrating planetary health into infection prevention and control in healthcare settings-towards a balanced and evidence-based approach.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same author

LVAD specific infection with Coxiella burnetii treated with heart transplantation and antibiotic suppression.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2026
Same author

How to get cheap clean air? Implementation of an affordable high-efficient air filtration ventilation system for operating theatres in a low-resource setting.

GMS hygiene and infection control·2026
Same author

A cross-specialty, evidence-based Delphi consensus of a care bundle to reduce surgical site infections.

International journal of surgery (London, England)·2026
Same journal

Use of gloves: current evidence vs. current use.

Current opinion in infectious diseases·2026
Same journal

Understanding challenges to prevention of healthcare related infections.

Current opinion in infectious diseases·2026
Same journal

Harnessing next-generation microbial diagnostics to optimize infection management in immunocompromised hosts.

Current opinion in infectious diseases·2026
Same journal

Epidemiology, treatment and outcomes of antimicrobial-resistant infections in hematopoietic stem cell transplant recipients.

Current opinion in infectious diseases·2026
Same journal

Dengue and chikungunya vaccines past, present and future: implications for travelers.

Current opinion in infectious diseases·2026
Same journal

Oropouche virus: viral evolution, epidemiological trends, and challenges for control.

Current opinion in infectious diseases·2026
See all related articles

This review covers new strategies for preventing, diagnosing, and treating infections linked to joint prostheses and internal fixation devices. Advances include improved diagnostics and tailored treatments for implant-associated infections.

Area of Science:

  • Orthopedic surgery
  • Infectious diseases
  • Biomaterials science

Background:

  • Implant-associated infections pose significant challenges in orthopedic surgery.
  • Joint prostheses and internal fixation devices are susceptible to microbial colonization and biofilm formation.

Purpose of the Study:

  • To review recent advancements in the prevention, diagnosis, and treatment of infections related to orthopedic implants.
  • To highlight novel diagnostic techniques and therapeutic strategies for implant-associated infections.

Main Methods:

  • Review of current literature on perioperative antimicrobial prophylaxis.
  • Analysis of emerging diagnostic tools such as implant sonication and molecular techniques.
  • Evaluation of treatment strategies, including device retention and antimicrobial regimens.

Related Experiment Videos

  • Assessment of novel antimicrobial agents and their potential applications.

    • Main Results:

    • Optimized timing for perioperative antimicrobial prophylaxis is critical.
    • Implant sonication and molecular methods enhance diagnostic accuracy for biofilm-related infections.
    • Treatment without device removal is viable for select cases, with rifampin combinations being key for staphylococcal infections.
    • Emerging agents like dalbavancin and tigecycline show promise, but antimicrobial resistance necessitates ongoing research into alternative therapies.

    Conclusions:

    • A deeper understanding of host-pathogen-implant interactions is vital for improving management.
    • Treatment decisions for implant-associated infections should be individualized based on infection duration, implant stability, pathogen susceptibility, and soft tissue condition.