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Complications of CAPD in children: six years experience in Caracas, Venezuela
Insights
Children with end-stage renal disease (ESRD) on continuous ambulatory peritoneal dialysis (CAPD) experienced higher peritonitis rates linked to lower socioeconomic status. These findings suggest hemodialysis may be preferable for low socioeconomic status ESRD patients.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
- Public Health
Background:
- Continuous ambulatory peritoneal dialysis (CAPD) is a treatment for pediatric end-stage renal disease (ESRD).
- Socioeconomic status may influence treatment outcomes in ESRD patients.
Purpose of the Study:
- To evaluate the incidence of complications in children with ESRD treated with CAPD.
- To investigate the correlation between socioeconomic status and peritonitis rates in pediatric CAPD patients.
Main Methods:
- A retrospective study of 43 children with ESRD treated with CAPD from November 1984 to July 1990.
- Analysis of complication rates, including peritonitis, infections, and catheter malfunctions.
- Assessment of socioeconomic status using the Graffar Index (G.I.).
Main Results:
- The overall peritonitis rate was one episode per 5.6 patient-months.
- A significant correlation was observed between lower socioeconomic status (G.I. IV-V) and higher peritonitis incidence (1 episode per 2.9 patient-months).
- Other complications included exit site infections, tunnel abscesses, catheter obstructions, and hernias.
Conclusions:
- Patients with very low socioeconomic status are at higher risk for peritonitis during CAPD.
- Hemodialysis may be a more suitable treatment option for pediatric ESRD patients with low socioeconomic status.
Abstract:
Forty-three ESRD children received treatment with CAPD from November 1984 through July 1990. Mean patient age was 10 years (range 2-17 years) and total observation period (consolidated for the whole group) was 683 months. Double cuff Tenckhoff catheters were used as access. The most common complication was peritonitis with an overall rate of one episode per 5.6 patient/months. Important correlation was found between incidence of peritonitis and socioeconomic status assessed by Graffar Index (G.I.). Patients with lowest socioeconomic status (GI of IV and V) had one episode of peritonitis per 2.9 patient/months. Patients with GI of III had one episode per 5.2 patient/months and patients with the best socioeconomic status (GI of I and II) had only one episode per 11.6 patient/months. Other complications were the following: Infections: 18 exit site infection, 5 exit site granuloma and 5 tunnel abscess. Catheter malfunction: 17 obstructions, 5 migrations and 2 ruptures. Others: 3 peritoneal hemorrhages, 1 intestinal perforation, 3 eventrations, 4 inguinal hernias and 1 right pleural effusion. In this last patient, pleurodesis was unsuccessfully attempted with homologous blood. We conclude that patients with very low socioeconomic status are poor candidates for CAPD and should be considered preferably for hemodialysis.
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