Comparison of resting energy expenditure in bronchopulmonary dysplasia to predicted equation

L Bott1, L Béghin, C Marichez

  • 1Unité de Gastroentérologie, Hépatologie et Nutrition, Clinique de Pédiatrie, Hôpital Jeanne de Flandre, Lille, France.

Insights

Resting energy expenditure (REE) prediction equations can help manage growth failure in children with bronchopulmonary dysplasia (BPD). The Harris-Benedict equation accurately estimated REE in BPD children, aiding nutritional support.

Area of Science:

  • Pediatric Nutrition
  • Respiratory Medicine
  • Metabolic Research

Background:

  • Children with bronchopulmonary dysplasia (BPD) often experience growth failure due to altered energy balance and increased resting energy expenditure (REE).
  • Accurate REE evaluation is crucial for effective nutritional management in these children.
  • Indirect calorimetry, the gold standard for REE measurement, is complex and time-consuming.

Purpose of the Study:

  • To assess the accuracy of various prediction equations for estimating REE in children with BPD.
  • To compare the performance of four established REE prediction equations against indirect calorimetry.

Main Methods:

  • Fifty-two children (aged 4-10 years) diagnosed with BPD and 30 healthy children were included.
  • Indirect calorimetry was used as the reference method to measure REE.
  • Four prediction equations (Schofield-W, Schofield-HW, Harris-Benedict, and FAO) were evaluated using Bland-Altman analysis.

Main Results:

  • The Harris-Benedict equation demonstrated the best agreement for predicting REE in children with BPD (mean difference: 15 kcal/day).
  • For healthy children, the Schofield-W equation showed the best agreement (mean difference: -2.9 kcal/day).
  • Prediction equations offer a practical alternative to indirect calorimetry, with minimal differences in outcomes.

Conclusions:

  • Prediction equations can be a valuable tool for managing REE in children with BPD.
  • The Harris-Benedict equation is recommended for estimating REE in pediatric BPD patients.
  • These equations simplify the nutritional assessment process for children with chronic lung disease.
Abstract

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