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Published on: September 22, 2020
[Primary angioplasty for acute myocardial infarction in octogenarian patients]
Ran Kornowski1, Igal Teplitsky, David Brosh
1Catheterization Laboratories, Cardiology Department, Rabin Medical Center, Petach Tikva, Israel. rkornowski@clalit.org.il
Insights
Primary angioplasty is feasible for octogenarian patients with ST-elevation myocardial infarction. However, elderly patients face higher 30-day mortality and major cardiac events compared to younger individuals.
Area of Science:
- Cardiology
- Geriatric Medicine
- Interventional Cardiology
Context:
- Acute myocardial infarction (AMI) is a critical cardiovascular event.
- Primary angioplasty is a standard treatment for ST-elevation myocardial infarction (STEMI).
- Outcomes in elderly populations, particularly octogenarians, require specific evaluation.
Purpose:
- To assess the clinical outcomes of octogenarian patients undergoing primary angioplasty for STEMI.
- To compare the 30-day mortality and major cardiac events between octogenarian and younger STEMI patients treated with primary angioplasty.
Summary:
- This study analyzed clinical data from patients treated with primary angioplasty for STEMI within 12 hours, excluding those in cardiogenic shock.
- Octogenarian patients (>= 80 years) demonstrated significantly higher 30-day mortality (12% vs. 3.3%) and major cardiac events (17.5% vs. 7.4%) compared to younger patients (< 80 years).
- Primary angioplasty is feasible and relatively safe in octogenarians, but outcomes are less favorable than in younger cohorts.
Impact:
- Highlights the increased risks associated with primary angioplasty in octogenarian STEMI patients.
- Informs clinical decision-making and risk stratification for elderly patients undergoing percutaneous coronary intervention.
- Underscores the need for tailored management strategies to improve outcomes in this vulnerable demographic.
Abstract:
This study aimed to evaluate clinical outcomes in octogenarian patients with acute myocardial infarction (AMI) treated by primary angioplasty. We used our clinical database consisting of all patients treated using primary angioplasty (< or = 12 hours) for acute ST elevation myocardial infarction excluding patients with cardiogenic shock. The clinical and angiographic results of non-shock patients, distinguished according to age < 80 years and > or = 80 years, was characterized by higher 30-day mortality among the elderly compared to younger patients (12% versus 3.3%) and overall major cardiac events (17.5% versus 7.4%). Thus, primary angioplasty in the octogenarian patients, albeit feasible and relatively safe, is associated with 30-days death rates that are higher in octogenarian patients as compared to younger patients.
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