Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optimisation of thyroid hormone replacement using an automated thyroid register.

D J Cuthbertson1, R Flynn, R T Jung

  • 1Department of Diabetes and Endocrinology, Ninewells Hospital and Medical School, Dundee, Tayside, Scotland. d.j.r.cuthbertson@dundee.ac.uk

International Journal of Clinical Practice
|June 30, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment and management of acute epididymo-orchitis in the emergency department.

Irish medical journal·2025
Same author

Bayesian networks and imaging-derived phenotypes highlight the role of fat deposition in COVID-19 hospitalisation risk.

Frontiers in bioinformatics·2023
Same author

Poor glycaemic control and ectopic fat deposition mediates the increased risk of non-alcoholic steatohepatitis in high-risk populations with type 2 diabetes: Insights from Bayesian-network modelling.

Frontiers in endocrinology·2023
Same author

Dynapenic Abdominal Obesity as a Risk Factor for Falls.

The Journal of frailty & aging·2023
Same author

Calcium requests in a primary care; An observational audit of biochemical requests and frequency of abnormal results.

Clinical biochemistry·2022
Same author

A Comparison of Urology Service Provision Between the First and the Third Waves of the COVID-19 Pandemic.

Irish medical journal·2022

Thyroid dysfunction management improved since 1991, reducing suppressed thyroid-stimulating hormone (TSH) levels in hypothyroidism treatment. Hyperthyroidism treatment shifted towards radioiodine, away from thyroidectomy, without impacting outcomes.

Area of Science:

  • Endocrinology
  • Thyroidology
  • Public Health

Background:

  • Thyroid dysfunction is prevalent, necessitating effective monitoring and treatment adjustment.
  • Thyroid hormone replacement and hyperthyroidism treatments require careful management to avoid adverse effects.

Purpose of the Study:

  • To evaluate the precision of thyroxine replacement in hypothyroidism.
  • To assess changes in hyperthyroidism treatment trends since 1991.
  • To analyze the impact of these changes on patient outcomes.

Main Methods:

  • Comparative analysis of patient data from a network of 12,524 individuals with thyroid dysfunction.
  • Examination of register data from before and after 1991.
  • Assessment of thyroid-stimulating hormone (TSH) levels, radioiodine use, and thyroidectomy rates.

Related Experiment Videos

Main Results:

  • A significant reduction in TSH suppression in thyroxine-treated patients from 58.5% to 9.2% post-1991.
  • Increased radioiodine use (14.3%) and decreased thyroidectomy use (12.3%) for hyperthyroidism post-1991.
  • No significant differences in subsequent hypothyroidism rates or mean thyroxine dosage between hyperthyroidism treatments.

Conclusions:

  • Thyroid management strategies have evolved, leading to improved TSH control in hypothyroidism.
  • Treatment preferences for hyperthyroidism have shifted, with radioiodine becoming more common.
  • Current treatment adjustments appear effective and do not negatively impact long-term outcomes.