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Related Experiment Video

Updated: Jul 19, 2026

Treatment of Ejaculatory Duct Obstruction by Seminal Vesiculoscopy Assisted Flow Modification

Treatment of Ejaculatory Duct Obstruction by Seminal Vesiculoscopy Assisted Flow Modification

Published on: December 8, 2023

Treatment of premature ejaculation.

A Riley¹, R T Segraves

¹Lancashire School of Health and Postgraduate Medicine, University of Central Lancashire, Preston, UK. alanriley@doctors.org.uk

International Journal of Clinical Practice

|June 30, 2006

Summary

Premature ejaculation (PE) management includes psychotherapy and local anesthetics. Selective serotonin reuptake inhibitors are effective for delaying ejaculation but lack specific PE licensing and show high relapse rates.

Area of Science:

Urology
Andrology
Sexual Medicine

Background:

Premature ejaculation (PE) is a prevalent sexual dysfunction.
Management strategies for PE have evolved over time.
Current treatments aim to delay ejaculation and improve control.

Purpose of the Study:

To review current and emerging treatments for premature ejaculation.
To evaluate the efficacy and limitations of various PE management options.

Main Methods:

Review of traditional psychotherapeutic techniques (e.g., squeeze, stop-start).
Analysis of topical anesthetic applications for delaying ejaculation.
Examination of psychopharmacological agents, particularly antidepressants, for PE treatment.

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Main Results:

Selective serotonin reuptake inhibitors (SSRIs) demonstrate the highest efficacy in delaying ejaculation among psychopharmacological agents.
No SSRIs are currently licensed specifically for the treatment of PE.
High relapse rates are observed across various therapeutic modalities for PE.

Conclusions:

SSRIs are the most effective agents for delaying ejaculation in PE, despite lacking specific licensing.
Further research is needed to develop licensed and sustainable treatments for PE.
High relapse rates necessitate ongoing management strategies for PE patients.