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Related Experiment Videos

Pyrexia following total knee replacement.

Subhajit Ghosh1, Richard M Charity, Saadallah G Haidar

  • 1Department of Trauma and Orthopaedic Surgery, City Hospital, Dudley Road, Birmingham B18 7QH, UK.

The Knee
|June 30, 2006
PubMed
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Post-total knee replacement (TKR) fever is common, with 36.5% of patients experiencing it. This pyrexia is typically a normal physiological response, not indicative of infection after TKR.

Area of Science:

  • Orthopedic Surgery
  • Postoperative Care
  • Infectious Disease Epidemiology

Background:

  • Fever is a common concern following total knee replacement (TKR).
  • Distinguishing physiological fever from infection-related fever is crucial for patient management.
  • Understanding the incidence and predictors of pyrexia post-TKR is essential.

Purpose of the Study:

  • To determine the incidence of pyrexia after total knee replacement (TKR).
  • To identify factors associated with pyrexia following TKR.
  • To evaluate the diagnostic utility of pyrexia for detecting infection post-TKR.

Main Methods:

  • Retrospective analysis of temperature charts and patient histories.
  • Inclusion of 170 patients who underwent total knee replacement (TKR).

Related Experiment Videos

  • Statistical analysis to assess temperature changes and associations.

    • Main Results:

    • A significant increase in mean body temperature was observed post-TKR, persisting for 5 days.
    • Pyrexia (≥38°C) occurred in 36.5% of patients.
    • No significant association was found between pyrexia and infection, blood transfusion, hemoglobin loss, urinary catheter use, rheumatoid arthritis, anesthetic type, or prior pyrexia.
    • Pyrexia demonstrated low sensitivity (28.6%) and low positive predictive value (6.5%) for infection detection.

    Conclusions:

    • Postoperative pyrexia within the first 5 days after TKR is generally a normal physiological response.
    • Pyrexia alone should not be a primary indicator of clinical infection following TKR.
    • Clinical judgment remains paramount in diagnosing infection in TKR patients.