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Updated: Aug 7, 2026
Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology
Published on: August 23, 2024
Release of alpha-tocopherol from antioxidative low-density polyethylene film into fatty food simulant: influence of
1Faculty of Food Science, Department of Preservation, Corvinus University of Budapest, Ménesi út 45, H-1118 Budapest, Hungary. istvan.siro@uni-corvinus.hu
Abstract:
The release of alpha-tocopherol from two formulations (with and without complexation with beta-cyclodextrin) of low-density polyethylene (LDPE) film was examined. Specific migration studies were performed at 7.0 +/- 0.5 degrees C using plastic bags filled with 95% ethanol as a fatty food simulant. The amount of complexed and free (non-complexed) alpha-tocopherol migrating into the food simulant was followed by high-performance liquid chromatography (HPLC). It was concluded that complexation with beta-cyclodextrin had a significant effect on the release rate of the antioxidant. Using a mathematical model for the description of the migration, a decrease in diffusion coefficient (D) of one order of magnitude was calculated in the case of complexed alpha-tocopherol compared with the free form. Total migration of alpha-tocopherol from both films was observed, meaning that the partition coefficient of tocopherol was not influenced by incorporation with cyclodextrin. Thus, complexation might be the key to a long-lasting antioxidative effect of such kind of active packaging.
