Related Experiment Video
Updated: Aug 7, 2026

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
Does endoluminal coil embolization cause distension of intracranial aneurysms?
Simon C H Yu1, Wilbur C K Wong, Albert C S Chung
1Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Shatin, NT Hong Kong, People's Republic of China. simonyu@cuhk.edu.hk
Introduction:
The aim of the present study was to determine whether intracranial aneurysms are distended after coil embolization and to evaluate the distensibility of ruptured aneurysms treated with endovascular coiling.
Methods:
This was a prospective study of 20 consecutive patients with 22 aneurysms, who presented with a ruptured cerebral aneurysm and were treated with endovascular coiling of the aneurysm in a single institution. A diagnostic digital subtraction angiography (DSA) and a three-dimensional radiographic angiography (3DRA) were performed with bi-plane angiography equipment (Philips V5000) immediately before and after the embolization procedure to detect volume enlargement of the aneurysm after embolization, and the extent of the enlargement. A simulation study with steel spheres was carried out to study the possible error of over-estimation of the postembolization volume due to the beam-hardening artifact.
Results:
There was no procedure-related rupture of the aneurysms. The percentage by volume of solid coil within the coil mass ranged from 15.78% to 82.01% in the present series. All aneurysms showed distension which ranged from 0.09% to 34.23%. The distensibility of the aneurysms was 34.23%. Error due to the beam-hardening artifact was negligible.
Conclusion:
Endoluminal packing of intracranial saccular aneurysms with embolization coils could cause a certain degree of distension in aneurysms treated with coil embolization, with the degree of distension up to 34.2%. Intracranial aneurysms were able to tolerate a certain degree of endoluminal distension without a risk of immediate rupture, even those that had ruptured recently.
Related Concept Videos
Aneurysm I: Introduction
Aneurysm IV: Nursing Management
Aneurysm III: Interprofessional Care
Increased Intracranial Pressure ll: Pathophysiology
Cerebral Edema l: Introduction
Aneurysm II: Clinical Manifestations and Diagnostic Studies

