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Related Experiment Videos

Layer manufacturing for in vivo devices.

M M Savalani1, R A Harris

  • 1Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, Loughborough, Leicestershire, UK.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
|July 1, 2006
PubMed
Summary

Rapid manufacturing (RM) offers advanced techniques for creating complex in vivo devices, overcoming limitations of traditional methods. This approach enables greater functionality and customization for medical implants and tissue scaffolds.

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Manufacturing Technology

Background:

  • Traditional in vivo devices like sutures and implants are made using machining and molding.
  • These methods have limitations in lead time, geometric complexity, and customization.
  • Regenerative medicine and drug delivery drive the need for complex, novel in vivo devices such as tissue scaffolds.

Purpose of the Study:

  • To explore rapid manufacturing (RM) and biomanufacturing based on layer manufacturing techniques.
  • To address limitations of conventional fabrication methods for in vivo devices.
  • To investigate new materials and production techniques for advanced in vivo devices.

Main Methods:

  • Review of traditional and advanced fabrication techniques for in vivo devices.

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  • Identification of layer manufacturing concepts for biomanufacturing.
  • Emphasis on material development and computer modeling for bio-RM.

    • Main Results:

    • Layer manufacturing techniques offer solutions to geometric limitations and long lead times.
    • Existing methods for non-conventional devices lack control over internal architecture and composition.
    • Rapid manufacturing provides a pathway for economically producing customized in vivo devices.

    Conclusions:

    • Freeform layer manufacturing techniques are being investigated to overcome fabrication challenges.
    • Bio-RM holds promise for developing in vivo devices with enhanced functionality and customization.
    • Further research into materials, production techniques, and modeling is crucial for advancing bio-RM.