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Published on: December 18, 2010
Abdominal aortitis due to Streptococcus pneumoniae and Enterobacter aerogenes: a case report and review
Matthew T Rondina1, Kalani Raphael, Robert Pendleton
1Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA. matthew.rondina@hsc.utah.edu
Abstract:
Endovascular infections are 1 cause of fever of unknown origin. We describe a diagnostically challenging case of cryptogenic abdominal aortitis from Streptococcus pneumoniae and Enterobacter aerogenes. A 72-year-old male presented with epigastric pain, fevers, and chills. A computed tomography scan demonstrated enlargement and ulceration of the distal abdominal aorta, prompting urgent vascular surgery. Intraoperative tissue cultures grew S. pneumoniae and E. aerogenes and gatifloxacin was administered for 6 weeks. Spontaneous abdominal aortitis is uncommon and usually due to a single pathogen. This is the second reported case of polymicrobial infectious aortitis and to date, Enterobacter has only been reported in infected aortic grafts. Clinicians should maintain a high index of suspicion for infectious aortitis as the mortality, if only treated medically, approaches 100%.
Insights
This case study highlights a rare polymicrobial infectious aortitis caused by Streptococcus pneumoniae and Enterobacter aerogenes. Early surgical intervention and antibiotics are crucial for treating this life-threatening condition.
Area of Science:
- Infectious Diseases
- Vascular Surgery
- Microbiology
Background:
- Endovascular infections are a significant cause of fever of unknown origin.
- Infectious aortitis, particularly spontaneous abdominal aortitis, is uncommon and often presents diagnostic challenges.
Observation:
- A 72-year-old male presented with epigastric pain, fever, and chills.
- Computed tomography revealed an enlarged and ulcerated distal abdominal aorta, necessitating urgent vascular surgery.
- Intraoperative cultures identified Streptococcus pneumoniae and Enterobacter aerogenes.
Findings:
- This case represents the second reported instance of polymicrobial infectious aortitis.
- Enterobacter species have previously been documented primarily in infected aortic grafts.
- The patient received a 6-week course of gatifloxacin post-surgery.
Implications:
- Clinicians must maintain a high index of suspicion for infectious aortitis due to its high mortality rate if treated non-surgically.
- This case expands the understanding of polymicrobial involvement in spontaneous aortitis.
- Prompt diagnosis and combined surgical and antimicrobial therapy are essential for favorable outcomes.
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