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Hematoma size in deep intracerebral hemorrhage and its correlation with dot-like hemosiderin spots on gradient echo

Toshio Imaizumi1, Toshimi Honma, Yoshifumi Horita

  • 1Department of Neurosurgery, Kushiro City General Hospital, 1-12 Shunkodai, Kushiro, Hokkaido 085-0822, Japan. timaizum@d9.dion.ne.jp

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
|July 1, 2006
PubMed
Abstract

Insights

The number of dot-like hemosiderin spots (dotHSs) on MRI may indicate smaller deep intracerebral hemorrhages (ICH). More dotHSs were associated with smaller ICH diameters, suggesting they might represent microbleeds that don't enlarge to symptomatic size.

Area of Science:

  • Neurology
  • Radiology
  • Pathology

Background:

  • Dot-like hemosiderin spots (dotHSs) on MRI indicate old cerebral microbleeds.
  • These spots are linked to small vessel fragility and bleeding tendencies.

Purpose of the Study:

  • To investigate the relationship between dotHSs and the size of primary deep intracerebral hemorrhage (ICH).
  • To determine if the number of dotHSs correlates with ICH diameter.

Main Methods:

  • Analyzed dotHS diameter and number in 151 patients with deep ICH.
  • Used multivariate analysis to estimate hazard ratios for ICH size based on dotHS count and stroke risk factors.

Main Results:

  • Patients with deep ICH diameter <= 2 cm had significantly more dotHSs (9.2 +/- 11.5) compared to those with ICH > 2 cm (4.7 +/- 7.0).
  • Multivariate analysis showed dotHSs were associated with a smaller maximal ICH diameter (HR, 3.7; P = .009).

Conclusions:

  • The number of dotHSs may be associated with smaller deep ICH.
  • Further research with larger sample sizes is needed to confirm these findings.

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