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Updated: Aug 7, 2026
Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
Multifocal osteosarcoma involving unusual sites
Manisha Bhutani1, Ashutosh Kumar Pathak, Manju Sengar
1Department of Medical Oncology, Institute Rotary Cancer Hospital, New Delhi, India. mbhutani@mdanderson.org
Abstract:
We report a rare case of multifocal osteosarcoma (MFOS) with involvement of skeleton, lung, bone marrow, and soft tissues, presenting with paraparesis, cranial nerve palsies, subcutaneous nodules, anemia, and thrombocytopenia. MFOS with involvement of unusual sites presents problems in diagnosis and has a poor prognosis. The literature on 11 cases of MFOS with extraosseus, extrapulmonary involvement reported previously has been reviewed.
