A pilot randomized control study to evaluate endoscopic resection using a ligation device for rectal carcinoid...

Area of Science:

• Gastroenterology
• Surgical Oncology
• Endoscopic Surgery

Background:

• Rectal carcinoid tumors smaller than 10 mm are typically treated with local excision.
• Complete tumor removal is crucial for successful treatment and preventing recurrence.

Purpose of the Study:

• To evaluate the efficacy and safety of endoscopic mucosal resection with a ligation device for complete removal of small rectal carcinoid tumors.
• To compare this novel technique with conventional endoscopic resection.

Main Methods:

• A pilot randomized study involving 15 patients with rectal carcinoid tumors (3-10 mm).
• Patients were randomly assigned to either conventional endoscopic resection (7 patients) or endoscopic resection using a ligation device (8 patients).
• Tumor location, size, and patient characteristics were recorded. Complete removal rates and complications were assessed.

Main Results:

• The ligation device group achieved a 100% complete tumor removal rate (8/8).
• Conventional endoscopic resection resulted in a 57.1% complete removal rate (4/7).
• Three patients in the conventional group had deep margin involvement, requiring additional treatment. No complications were observed in either group.

Conclusions:

• Endoscopic resection using a ligation device is a highly effective and safe method for achieving complete resection of small rectal carcinoid tumors.
• This technique offers a significant advantage over conventional endoscopic resection in terms of complete tumor removal rates.