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Published on: March 6, 2019

Bronchopulmonary moniliasis in the newborn

A Linhartová1, W Chung

  • 1Sikl Institute of Pathological Anatomy, Charles University, Plzen, Czechoslovakia.

Journal of Clinical Pathology
|January 1, 1963
PubMed

Insights

Bronchopulmonary moniliasis, a fungal infection in newborns caused by Candida albicans, occurred in 1.05% of neonates. Aspiration after birth, not maternal infection, is the likely transmission route.

Area of Science:

  • Medical Mycology
  • Neonatal Pathology
  • Infectious Diseases

Background:

  • Bronchopulmonary moniliasis is a serious fungal infection in neonates.
  • Candida albicans is a common cause of opportunistic infections.

Purpose of the Study:

  • To describe ten cases of bronchopulmonary moniliasis in neonatal infants.
  • To investigate the incidence and potential transmission routes of this infection.

Main Methods:

  • Morphological identification of Candida albicans.
  • Analysis of necropsy data from 947 neonates.

Main Results:

  • Ten cases of bronchopulmonary moniliasis were identified in infants aged 1-11 days.
  • The incidence was 1.05% of all neonate necropsies.
  • Seven cases showed inflammation; three did not.
  • Aspiration post-delivery was identified as the primary transmission mechanism over maternal vaginitis.

Conclusions:

  • Bronchopulmonary moniliasis is a significant finding in neonatal necropsies.
  • Aspiration is the predominant route of infection, challenging the emphasis on maternal transmission.

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