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Related Experiment Videos

Bladder function and dysfunction in exstrophy and epispadias.

J G Hollowell1, P D Hill, P G Duffy

  • 1Department of Paediatric Urology, St Peter's Hospitals, London, UK.

Lancet (London, England)
|October 12, 1991
PubMed
Summary
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Bladder exstrophy and epispadias evaluation reveals impaired bladder function after surgery. Detailed functional testing is crucial for managing these congenital urinary tract abnormalities.

Area of Science:

  • Pediatric Urology
  • Congenital Abnormalities
  • Lower Urinary Tract Function

Background:

  • Bladder exstrophy and epispadias are congenital urinary tract abnormalities.
  • Previous bladder function evaluation before and after reconstruction is limited.
  • Optimal treatment strategies require better understanding of bladder function.

Purpose of the Study:

  • To prospectively evaluate lower urinary tract function in children with bladder exstrophy and epispadias.
  • To assess bladder function before and after bladder-neck reconstruction.
  • To identify factors contributing to persistent urinary leakage and upper urinary tract damage.

Main Methods:

  • Prospective study of 36 children (1.5–16 years) with bladder exstrophy and epispadias.

Related Experiment Videos

  • Lower urinary tract function assessed by cystometry and cystography.
  • Upper urinary tract evaluation using ultrasound imaging.

    • Main Results:

    • Normal bladder function observed in primary epispadias cases.
    • Conventional bladder-neck surgery for continence severely impaired bladder function.
    • Involuntary bladder contractions identified as a cause of persistent urine leakage.
    • Abnormalities may hinder bladder capacity development and cause upper urinary tract damage.

    Conclusions:

    • Conventional bladder-neck surgery may not be the optimal treatment for bladder exstrophy and epispadias.
    • Closed exstrophy bladders do not achieve normal function.
    • Involuntary bladder contractions are a significant issue post-surgery.
    • Routine detailed functional testing is recommended for these patients.