[Phosphor/sulphur ratio: indicator of malignant uterine changes]

The purpose of the present study was to find a correlation between gynaecological diseases--myoma (26), adenocarcinoma uteri (21) - and P/S (phosphor/sulphur) ratios of different regions of uterus. Routine histological specimens were re-examined with the intention to select representative regions of the uteruses for element analysis. Conventional haematoxylineosin stained sections were used to identify histological alterations by light microscopy. Energy-dispersive spectroscopic (EDS) investigations were carried out to analyse the morphology and the related element composition of the samples. The results of the non-parametric statistical test (Wilcoxon two-sample test) indicate that the P/S ratios were significantly higher in adenocarcinoma (0.8891 +/- 0.0757) than in myoma (0.4713 +/- 0.0306). P/S ratio of different pathologic regions of uteruses seems worth examining in a larger study population.