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Patient with double cancer--successfully treated
V B Djukić1, D A Kastratović, I P Pendjer
1Institute of Othorhynolaringology and maxillofacial surgery.
Acta Chirurgica Iugoslavica
|July 4, 2006
Summary
Thrombocytosis and idiopathic thrombosis may indicate hidden cancers, particularly in head and neck tumors. Anticoagulant therapy is suggested to prevent complications and potentially reduce mortality rates.
Area of Science:
- Oncology
- Hematology
- Medical Diagnostics
Background:
- Thrombosis in cancer patients is multifactorial, involving tumor procoagulants, immobility, infections, and cancer treatments.
- Thrombocytosis is frequently observed in various malignancies.
Observation:
- A 53-year-old female with hypopharyngeal cancer and metastasis presented with deep leg vein thrombosis and pseudomonas infection.
- Persistent thrombocytosis led to the diagnosis of a secondary Choroidal Malignant Melanoma.
- The patient received surgical treatment, antibiotics, anticoagulants, and radiotherapy.
Findings:
- The co-occurrence of thrombocytosis and idiopathic thrombosis can be indicative of occult malignancy.
- This case highlights the diagnostic challenge and potential link between thrombotic events, thrombocytosis, and head and neck cancers.
Implications:
- Further research is warranted to explore the relationship between thrombosis, thrombocytosis, and head and neck tumors.
- Anticoagulants may prevent thromboembolic complications, inhibit angiogenesis, and reduce metastatic disease progression.
- Proactive management of thrombotic events could potentially lower cancer-related mortality rates.