Comparison of antitumor activities in tumor xenograft treatment
1Department of Biostatistics and Computational Biology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 630, Rochester, NY 14642, United States. hliang@bst.rochester.edu
Contemporary Clinical Trials
|July 4, 2006
Abstract:
To compare treatment effects with antitumor therapies, we proposed an intuitive approach to compare the antitumor effects of two different antitumor treatments by investigating tumor volumes which were measured in a given period of time. The approach is, in essence, a comparison of two unknown functions. The implementation of the approach is simple and straightforward. The approach is applied to analyze a real xenograft study of a new antitumor agent, irofulven, combined with irinotecan.
