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Pharmacokinetics of denopamine in hemodialysis patients
H Nakahama1, M Izumi, Y Tanaka
1First Department of Medicine Osaka University Medical School, Japan.
Renal Failure
|January 1, 1991
Abstract:
The pharmacokinetics of denopamine on a hemodialysis day and on an interdialysis day was evaluated in 11 hemodialysis patients. Tmax was the only pharmacokinetical parameter that differed significantly between healthy volunteers and hemodialysis patients. It is suggested that denopamine can be administered to hemodialysis both on hemodialysis days and on interdialysis days without dosage adjustments.