Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pleural liquid during hemorrhagic hypotension.

Claudio Tresoldi1, Cristina Porta, Luciano Zocchi

  • 1Istituto di Fisiologia Umana I, Università di Milano, Via Mangiagalli 32, 20133 Milano, Italy.

Respiratory Physiology & Neurobiology
|July 4, 2006
PubMed
Summary

Pleural fluid volume and pressure remain stable during moderate blood loss (25%). Significant changes in pleural fluid protein concentration occur only with severe blood loss (35%).

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combustion and Heated Tobacco Cigarettes, but Not E-Cigarettes, Impair Aquaporin-Dependent H<sub>2</sub>O<sub>2</sub> Permeability in ATII-Like Cells.

Cells·2026
Same author

Improving the Connection Between Population-Based and National Clinical Pediatric Cancer Registries-A Pilot Study on Neuroblastoma: The Italian BENCHISTA-Ita Project.

Cancers·2025
Same author

Effects of cigarette smoke extract on surfactant production in ATII-like cells, involvement of oxidative stress and autophagy.

Toxicology·2025
Same author

Gold Nanoparticles Decorated with HPLC6-Derived Peptides as a Platform for Ice Recrystallization Inhibition.

Biomacromolecules·2024
Same author

Molecular Impact of Conventional and Electronic Cigarettes on Pulmonary Surfactant.

International journal of molecular sciences·2023
Same author

Vitamin D Status and Parkinson's Disease.

Brain sciences·2022

Area of Science:

  • Physiology
  • Hemodynamics
  • Pleural Physiology

Background:

  • Hemorrhage significantly impacts physiological parameters.
  • The effects of blood loss on pleural fluid composition are not fully understood.

Purpose of the Study:

  • To investigate the impact of varying degrees of blood loss on pleural fluid dynamics and protein concentration.
  • To determine the threshold of blood loss affecting pleural fluid homeostasis in rabbits.

Main Methods:

  • Anesthetized rabbits underwent controlled hemorrhage (25% and 35% blood loss).
  • Pleural fluid volume, pressure, and protein concentration were measured.
  • Arterial plasma parameters and ventilation were monitored.

Main Results:

Related Experiment Videos

  • 25% blood loss did not alter pleural fluid volume or pressure.
  • 35% blood loss increased pleural fluid protein concentration by 85% and altered albumin/globulin ratios.
  • Ventilation increased with 25% blood loss but not with 35% blood loss.

Conclusions:

  • Pleural fluid is resilient to moderate hemorrhage (up to 25% blood loss) for short durations.
  • Severe hemorrhage (35% blood loss) significantly alters pleural fluid protein composition.
  • These findings highlight the protective mechanisms of pleural fluid during controlled blood loss.