[Vitamin D insufficiency in Japanese adults]
1Niigata University Graduate School of Medical and Dental Sciences, Department of Community Preventive Medicine.
Abstract:
Vitamin D insufficiency has recently drawn attention as a risk factor for osteoporosis. This paper evaluated vitamin D insufficiency in Japanese adults. The prevalence of vitamin D insufficiency, defined as serum 25-hydroxyvitamin D (25 [OH] D) concentrations less than 30 nmol/l, among independent community-dwelling elderly people was approximately five percent. Conversely, the prevalence of vitamin D insufficiency among frail, inactive elderly people with low levels of activities of daily living (ADL) was up to 50% greater. These results intimate that ADL may be an important determinant of vitamin D insufficiency. Overall findings highlight the need for measurement of serum 25 (OH) D to become a more common medical examination to detect vitamin D insufficiency in the elderly.
Related Concept Videos
Chronic Kidney Disease II: Clinical Manifestations
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Vitamins
Connective Tissue Cell Types
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...


