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Alternating bowel pattern: what do people mean?

R S Choung¹, G R Locke, A R Zinsmeister

¹Dyspepsia Center and Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN, USA.

Alimentary Pharmacology & Therapeutics

|July 5, 2006

Summary

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Defining an alternating bowel pattern is crucial for new therapies. This study found that alternating bowel patterns are a mix of constipation and diarrhea symptoms, not a distinct patient subgroup.

Area of Science:

Gastroenterology
Epidemiology
Clinical Medicine

Background:

Accurate patient subgrouping is vital for novel therapeutic strategies.
A clear definition of an alternating bowel pattern is currently lacking.

Purpose of the Study:

To identify specific symptoms associated with an alternating bowel pattern.
To clarify the characteristics of individuals reporting alternating bowel habits.

Main Methods:

Population-based surveys utilizing validated gastrointestinal symptom questionnaires.
Analysis of self-reported bowel patterns from a large, randomly selected community sample (n=2718).

Main Results:

7.6% of the study population reported an alternating bowel pattern.

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Key symptoms included incomplete evacuation (63%), urgency (57%), straining (55%), and loose stools (50%).

No symptom was exclusively reported by the alternating bowel pattern group.

Conclusions:

Individuals reporting alternating bowel patterns exhibit a combination of constipation and diarrhea symptoms.
The findings suggest that alternating bowel pattern is not a distinct clinical subgroup.