Related Experiment Video
Updated: Aug 7, 2026
An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum
Published on: January 26, 2024
Endometriosis mimicking advanced ovarian cancer
Anastasia Goumenou1, Ioannis Matalliotakis, Neal Mahutte
1Department of Obstetrics and Gynecology, University of Crete, Heraklion, Greece.
Objective:
To report a case of endometriosis associated with massive ascites, pleural effusion, and extremely elevated Ca-125.
Design:
Case report.
Setting:
University hospital.
Patient(S):
A 46-year-old, white nulligravida with bilateral adnexal masses, Ca-125 of 3,504 U/mL, abdominal pain, ascites, and a pleural effusion.
Intervention(S):
Chemotherapy followed by exploratory laparotomy for suspected ovarian cancer.
Main Outcome Measure(S):
Surgical findings and histopathology.
Result(S):
Intraoperative examination and histology ruled out malignancy but found stage IV endometriosis.
Conclusion(S):
In rare instances advanced endometriosis may be associated with ascites, pleural effusions, and large pelvic masses. For this reason endometriosis should be included in the differential diagnosis of reproductive-age women presenting with apparent ovarian malignancy.
