Related Experiment Video
Updated: Aug 7, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
Alcohol dependence in the 1990 US National Alcohol Survey: operationalizing and comparing two nosological systems
Abstract:
The criteria for alcohol dependence in both the ICD-10 and DSM-III-R nosologies were measured in a national general population survey, using 24 stem items and follow-ups. For current (12-month) dependence (at the criterion of 3+ components), the rate was 3.2% according to DSM-III-R criteria, and 5.4% according to ICD-10. The Kappa coefficient of agreement between the two systems for classification of individuals as currently dependent was 0.62, and for lifetime diagnosis the Kappa coefficient was 0.68. Prevalence for the individual components of each diagnosis and for the underlying items are given, and the contribution of each component to the overall dependence score is examined. Implications of the results for future epidemiological work with the two classifications are discussed.
More Related Videos
07:31Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
Published on: January 7, 2019
08:45Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis
Published on: November 8, 2024
Related Concept Videos
CNS Depressants: Alcohol and Nicotine
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Drug Abuse and Addiction: Pharmacological Phenomena
Drug Dependence
Diagnostic and Statistical Manual of Mental Disorders (DSM)
Hypothesis Test for Test of Independence
H0: The two variables (factors)...