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Updated: Aug 7, 2026

Determination of the Optimal Chromosomal Location(s) for a DNA Element in Escherichia coli Using a Novel Transposon-mediated Approach
Published on: September 11, 2017
The two Escherichia coli chromosome arms locate to separate cell halves
Xindan Wang1, Xun Liu, Christophe Possoz
1Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom.
Abstract:
DNA replication divides the circular Escherichia coli chromosome into equal arms (replichores). Visualization of pairwise combinations of multiple genetic loci reveals that the two replichores occupy separate nucleoid halves, with the replication origin between; positions of loci on each replichore recapitulate the genetic map. Sequential replication-segregation regenerates the
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