Related Experiment Video
Updated: Aug 7, 2026

A Mouse Model for Corneal Neovascularization by Alkali Burn
Published on: June 30, 2023
[Chemical injuries of the eye - management of alkali burns.]
Gunnar Már Zoega1, Jóhannes Kári Kristinsson
1Princess Alexandra Eye Pavillion, Chalmers Street, Edinburgh, EH4 3BY, Scotland. gmzoega@btinternet.com.
Abstract:
Chemical injuries are among the most severe injuries to the eye. Young men are most often affected. Work related injuries are more common than other types of injuries. Immediate treatment is paramount in preventing blindness. In the case of an alkali injury, an opaque cornea and a white edematous conjunctiva indicate a serious injury. In contrast, a clear cornea and a mildly to moderately irritated conjunctiva indicate a better prognosis. Copious irrigation is always the first treatment for all chemical injuries to the eye. Irrigation should be initiated as soon as possible and is to be continued until the tearfluid has regained a normal pH. Antibiotic ointment, lubrication and cycloplegic drops (e.g. Cyclogyl(R)) form the basis of treatment.
Related Concept Videos
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Pharmaceutical Poisoning: Treatment Strategies
Angle Closure Glaucoma: Treatment
Ophthalmic Drug Delivery Systems
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Accessory Structures of the Eye

