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Successful anticoagulation with bivalirudin in antithrombin-deficient pediatric patient undergoing stent placement

Rolando Zamora1

  • 1Pediatric Cardiology Associates, San Antonio, Texas 78229, USA. zamorasalinas@aol.com

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|July 5, 2006
PubMed

Many pediatric patients requiring anticoagulation during interventional heart catheterizations have antithrombin (AT) deficiency. AT is a necessary cofactor for heparin inhibition of thrombin. Without sufficient AT, these patients are at increased risk for thrombotic complications. This case describes the successful use of bivalirudin, a direct thrombin inhibitor, as an anticoagulant in a 2-month old infant with AT deficiency undergoing stent placement.

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