Related Experiment Video
Updated: Aug 7, 2026
Construction and Characterization of a Novel Vocal Fold Bioreactor
Published on: August 1, 2014
[The characteristic of vocal fold molecular structure]
Andrzej Obrebowski1, Waldemar Wojnowski, Zofia Obrebowska-Karsznia
1Katedra i Klinika Foniatrii i Audiologii AM im Karola Marcinkowskiego w Poznaniu.
Introduction:
The authors present the layer structure of the vocal fold (by Hirano) indicating at the same time its clinical usefulness in laser chordectomy.
Materials And Methods:
The authors describe the structure of the basement membrane sphere, i.e. the connection between the epithelium and the superficial layer of lamina propria, and the molecular structure of the extracellular matrix of mucosa.
Results:
The biomechanical significance of fibre proteins and the extracellular matrix is emphasized with special attention paid to hialuronic acid and fibronectin.
Conclusions:
Knowing the ultra-structure of the epithelium mucosa connection helps in understanding the mechanism of F0 production. The disorders in cooperation of the biomolecules of lamina propria of the vocal folds can influence the biomechanics of phonation.
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