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Updated: Aug 7, 2026

Concomitant Isolation of Primary Astrocytes and Microglia for Protozoa Parasite Infection
Published on: March 18, 2020
Central nervous system and eye manifestations of infection with Baylisascaris procyonis
Shira C Shafir1, Matthew E Wise, Frank J Sorvillo
1UCLA School of Public Health, Department of Epidemiology, Center for Health Sciences, Room 41-275, 650 Charles E. Young Drive, Los Angeles, CA 90024, USA. sshafir@ucla.edu
Abstract:
Baylisascaris procyonis, a parasitic infection of raccoons, causes severe neurologic and ocular disease in humans when infectious eggs from raccoon feces are ingested. In the absence of a serologic test, definitive diagnosis is challenging but can be made by isolation of larvae in brain biopsy, direct visualization of the worm in the eye, or exclusion of other potential causes of eosinophilic meningoencephalitis. Currently, no effective treatment has been identified, making preventive efforts critical.
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